α-Synuclein protein advances Parkinson’s by preventing neurons from clearing debris

nrn1199-f3

α-Synuclein impairs macroautophagy: implications for Parkinson’s disease JCB Home > 2010 Archive > 20 September > Winslow et al. 190 (6): 1023 Ashley R. Winslow1, Chien-Wen Chen1,3, Silvia Corrochano4, Abraham Acevedo-Arozena4, David E. Gordon2, Andrew A. Peden2, Maike Lichtenberg1, Fiona M. Menzies1, Brinda Ravikumar1, Sara Imarisio1,3, Steve Brown4, Cahir J. O’Kane3, and David C. Rubinsztein1 … Continue reading

Deep Brain Stimulation: Adenosine is crucial for DBS–mediated attenuation of tremor

Deep brain stimulation is a surgical treatment where electrodes, or brain pacemakers, are implanted into specific areas of the brain to drive an electrical jolt. The mechanism by which DBS results in the treatment of Parkinsons, Dystonia, Tremor, Chronic pain is still not clearly understood. DBS has been also used to treat tourettes, OCD, phantom … Continue reading

Investigating the neurobiology of music: BDNF modulation in the hippocampus of young adult mice.

Investigating the neurobiology of music: brain-derived neurotrophic factor modulation in the hippocampus of young adult mice. Behav Pharmacol. 2007 Sep;18(5-6):491-6. Angelucci F, Fiore M, Ricci E, Padua L, Sabino A, Tonali PA. Fondazione Don C. Gnocchi, Catholic University, Largo Gemelli, Rome, Italy. angeluccifrancesco@rm.unicatt.it Abstract It has been shown that music might be able to improve … Continue reading

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