Deep Brain Stimulation for Treatment-Resistant Depression causes drastic Improvement, not cure

Deep Brain Stimulation for Treatment-Resistant Depression: Follow-Up After 3 to 6 Years Sidney H. Kennedy, M.D., Peter Giacobbe, M.D., M.Sc., Sakina J. Rizvi, B.Sc., Franca M. Placenza, Ph.D., Yasunori Nishikawa, B.Sc., Helen S. Mayberg, M.D., and Andres M. Lozano, M.D., Ph.D. From the Department of Psychiatry and the Division of Neurosurgery, Department of Surgery, University … Continue reading

Neurogenic hippocampal targets of deep brain stimulation.

Neurogenic hippocampal targets of deep brain stimulation. J Comp Neurol. 2011 Jan 1;519(1):6-20. Encinas JM, Hamani C, Lozano AM, Enikolopov G. Cold Spring Harbor Laboratory, Cold Spring Harbor, New York 11724, USA. Deep brain stimulation (DBS) is being used to treat movement, neurological, and psychiatric disorders; recently it has been successfully applied to patients with … Continue reading

Music exposure differentially alters the levels of brain-derived neurotrophic factor and nerve growth factor in the mouse hypothalamus

Music exposure differentially alters the levels of brain-derived neurotrophic factor and nerve growth factor in the mouse hypothalamus Neuroscience Letters Volume 429, Issues 2-3, 18 December 2007, Pages 152-155 Francesco Angeluccia, Corresponding Author Contact Information, E-mail The Corresponding Author, Enzo Riccib, Luca Paduaa, Andrea Sabinob and Pietro Attilio Tonalia aFondazione Don C. Gnocchi, Rome, Italy … Continue reading

BDNF as a biomarker for mood disorders: an historical overview and future directions.

Brain-derived neurotrophic factor as a biomarker for mood disorders: an historical overview and future directions. Psychiatry Clin Neurosci. 2010 Aug;64(4):341-57. Hashimoto K. Division of Clinical Neuroscience, Chiba University Center for Forensic Mental Health, Chiba, Japan. hashimoto@faculty.chiba-u.jp Abstract Mood disorders, such as major depressive disorder (MDD) and bipolar disorder (BPD), are the most prevalent psychiatric conditions, … Continue reading

Resting State fMRI: A Novel Approach to Understanding Brain Dysfunction in Major Depression

A set of brain areas that are active at rest and share a similar timecourse of activity is shown. The top row represents the average “resting state network” from a group of 15 healthy controls, the middle row 14 schizophrenia patients, and the bottom row 17 bipolar disorder patients. It is clear that there are … Continue reading

Reading and controlling human brain activation using real-time functional magnetic resonance imaging (rt-fMRI)

Reading and controlling human brain activation using real-time functional magnetic resonance imaging R. Christopher deCharms Omneuron 3T MRI Research Center, Menlo Park, CA 94025, USA TRENDS in Cognitive Sciences Vol.11 No.11 ABSTRACT Understanding how to control how the brain’s functioning mediates mental experience and the brain’s processing to alter cognition or disease are central projects … Continue reading

MAP Kinase negative regulator [MKP-1] is a possible target for antidepressants

A PROTEIN involved in the growth and development of brain cells could play a role in depression and provide a possible target for antidepressants. Ron Duman and colleagues at Yale University began their search for a mechanism behind depression by comparing post-mortem brain samples from 21 people who had been depressed and 18 people of … Continue reading

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